- either the Doctor will not regenerate, or (unlikely) he "regenerates" by chance into the same body. This will have something to do with The Hand
- we will see Mickey the Idiot (c.f. the read-through scenes in Confidential), and possibly the Tyler family too
- Harriet Jones is not dead
- the Doctor will go back to the Time War
- We've had Bad Wolf, the Shadow Proclamations, and the Medusa Cascade. Is anything missing? At least we've cleared the decks of those for the Steve Moffatt era.
- Will Donna die?
- Will Donna's ring be significant?
- Is there something on Donna's back?
- Will things be resolved next week, or will the season end on a cliff-hanger related to this story? (presumably the next episode is the Christmas special, I think therefore that this story is unlikely to be continued straight away)
- Could next year's "specials" see the Doctor re-fighting the Time War?